DEPT
A DEPT spectrum is a more recent and more common way to get the same information that an off-resonance decoupled spectrum gives. DEPT is a Distortionless Enhanced Polarization Transfer experiment. DEPT keeps the peaks as single peaks so we do not lose as much signal and multiplets do not overlap.
Usually, a DEPT is run alongside a regular proton decoupled 13C NMR spectrum. It shows how many types of carbon atoms are in the molecule. In the DEPT, three different 13C NMR are shown. The DEPT-45, the bottom one in our example, shows a peak for all carbon atoms that have a hydrogen atom attached. Notice, the carbonyl, C, is not present in the DEPT-45. The DEPT-90 shows a peak for every C-H (one hydrogen atom attached) in our molecule. Notice, only the B carbon appears. Finally, the top spectrum, the DEPT-135, shows all carbon atoms with a hydrogen atom attached, but the carbon atoms with an odd number of hydrogen atoms, CH (B) and CH3 (E), point up while the CH2 peaks (A and D) point down. Quaternary carbon atoms, the carbonyl carbon C, do not appear.
DEPT-45: Carbon atoms with hydrogen atoms appear
DEPT-90: CH only appears
DEPT-135: CH and CH3 point up, CH2 points down.
11. Below is a DEPT spectrum for an organic compound. Which of the following compounds made this DEPT spectrum?
Answers
11. D. Notice the C=O peak and the symmetry with two types of CH2 groups.